Multi-agent architecture

The virtual R&D department

The orchestrator decomposes a product goal into research questions, simulations, formulation tasks, experiments and decision gates — then routes each to a specialist.

Orchestration flow

PRODUCT / RESEARCH GOAL
        │
   AI R&D ORCHESTRATOR
        │
  ┌─────┴─────┬────────────┐
Scientific  Computational  Product
Research    Science        Design
  └─────┬─────┴────────────┘
        ▼
  SAFETY ENGINE → REGULATORY ENGINE → LAB PLANNING
        ▼
  EXPERIMENTAL RESULTS → LEARNING LOOP → OPTIMIZED COMMERCIAL PRODUCT

Scientific Research

Turns objectives into graded, traceable evidence.

Literature Agent

Papers, trials, meta-analyses → graded evidence summaries

Target Biology Agent

Condition → pathways, genes, proteins, biomarkers

Patent Agent

Prior art, claim families, freedom-to-operate risk

Evidence Agent

Level A–E classification and contradiction detection

Computational Science

The molecular discovery engine, shared across all three verticals.

Protein Structure Agent

PDB / UniProt / AlphaFold prep and validation

Molecular Screening Agent

Library filtering and virtual screening funnel

Docking Agent

Pose generation, multi-engine rescoring

Molecular Dynamics Agent

RMSD, RMSF, contact and H-bond persistence

ADMET Agent

Absorption, metabolism, clearance, hERG, permeability

Toxicology Agent

Mutagenicity, sensitization, organ toxicity signals

Medicinal Chemistry Agent

Analogue design and iterative optimization

Product Design

Converts candidates into manufacturable, stable formulas.

Formulation Agent

Phase-structured formulas with process notes

Compatibility Agent

Ingredient interaction graph and incompatibility flags

Stability Agent

Degradation prediction and stability protocol design

Preservative Agent

Water activity, pH and coverage-based preservation

Dose Optimization Agent

Effective dose vs. feasibility and upper limits

Combination Optimization Agent

Synergy, redundancy, antagonism ranking

Skin Penetration Agent

Stratum corneum permeability and retention

Validation & Compliance

Keeps every recommendation auditable and human-approved.

DOE Agent

Factorial, response-surface and mixture designs

Experiment Planning Agent

Protocols, batch sizes, pass/fail criteria

Lab Results Agent

Prediction error tracking and model recalibration

Regulatory Agent

Region-specific limits and dossier assembly

Claims Compliance Agent

Claim wording risk before packaging

Product Classification Agent

Cosmetic vs. medicinal boundary detection

Audit & Traceability Agent

Input, model, version, approval chain of custody

Commercial

Makes R&D decisions commercially defensible.

Supplier Agent

Grades, MOQ, lead time, COA history

Cost Agent

COGS build-up and formula-vs-formula comparison

Competitor Intelligence Agent

Ingredient decks, claims, price and formula gaps

Product Innovation Agent

Unmet-opportunity generation with rationale

Manufacturing Readiness Agent

Equipment fit, scale-up and process risk

Agent decision framework

Agents never return unrestricted answers. Every recommendation carries its evidence, confidence, assumptions, risks and the experiment that would validate it.

Recommendation
Evaluate Compound A as a tyrosinase inhibitor.
Evidence
Docking + 200 ns MD + published in-vitro enzyme data.
Confidence
Moderate.
Assumptions
Active reaches the basal layer at formulated concentration.
Risks
No strong human topical study identified.
Validation required
Enzyme inhibition assay, then melanocyte assay.
Next experiment
EXP-4419 — mushroom tyrosinase IC50, 3 replicates.